论文标题

皮肤接触对刺激阈值和剂量法的影响

Effect of skin-to-skin contact on stimulation threshold and dosimetry

论文作者

Rashed, Essam A., Diao, Yinliang, Tanaka, Shota, Sakai, Takashi, Gomez-Tames, Jose, Hirata, Akimasa

论文摘要

电磁场暴露的人类剂量学是制定人为安全的暴露准则/标准以及产品安全评估的必不可少的任务。在从几百Hz到10 MHz的频率下,要保护的不利影响是刺激周围神经系统。皮肤中的原位电场用作神经激活的替代物。在低频剂量测定法中,在存在皮肤对皮肤接触的位置上有一个高但不准确的原位电场,其与刺激的关系是有争议的。高电场的原因之一可能归因于当前解剖模型的分辨率。在这项研究中,我们首先评估皮肤对皮肤接触的姿势的刺激阈值,以实验不同的手/指位置,以表示皮肤触摸/非触摸场景。我们确认皮肤接触不会降低引起疼痛所需的磁刺激装置的阈值电流。其次,提出了一种新方法,用于使用与实验相似的姿势的静态手部模型来配置不同的手指位置。我们计算皮肤对皮肤接触处的原位电场,以实现不同的手部姿势场景,这表明皮肤对皮肤区域的电场过多地升高,这是实验没有合理的。比较表明,皮肤中的原位电场高的原位电场是由皮肤层建模较差引起的,这还不足以在毫米的分辨率下代表。不应考虑这种皮肤对皮肤接触以在国际风险指南/标准以及产品安全评估中设置限制。

The human dosimetry for electromagnetic field exposure is an essential task to develop exposure guidelines/standards for human safety as well as product safety assessment. At frequencies from a few hundred Hz to 10 MHz, the adverse effect to be protected is the stimulation of the peripheral nervous system. The in situ electric field in the skin is used as a surrogate of nerve activation. In the low-frequency dosimetry, a high but inaccurate in situ electric field has been reported at positions where a skin-to-skin contact exists, whose relation to the stimulation is controversial. One of the reasons for high electric fields may be attributable to the current resolution of anatomical models. In this study, we first evaluate the stimulation threshold at postures of skin-to-skin contact experimentally for different hand/finger positions to represent skin touching/non-touching scenarios. We confirm that the skin-to-skin contact does not lower the threshold current of magnetic stimulation devices needed to induce pain. Second, a new method is proposed for hand modeling to configure different finger positions using static hand models with similar postures to the experiments. We compute the in situ electric field at skin-to-skin contact for the different hand posture scenarios that indicate an excessive raise of the electric field in skin-to-skin regions that is not justified by the experiments. The comparison suggests that a high in situ electric field in the skin would be caused by poor modeling of the skin layers, which is not enough to represent in a resolution of the order of a millimeter. This skin-to-skin contact should not be considered to set the restriction in the international exposure guidelines/standards as well as product safety assessment.

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