论文标题

Quaser-量子加速从头DNA序列重建

QuASeR -- Quantum Accelerated De Novo DNA Sequence Reconstruction

论文作者

Sarkar, Aritra, Al-Ars, Zaid, Bertels, Koen

论文摘要

在本文中,我们介绍了Quaser,这是通过基于门基和量子退火平台上从头组装的无参考的DNA序列重建实现。实施的四个步骤中的每个步骤(TSP,Qubo,Hamiltonians和Qaoa)都用简单的概念证明示例来解释,以独立的方式针对基因组学研究界和量子应用开发人员。讨论了量子全栈加速器设计的各个层的实现细节。我们还强调了当前经典模拟和可用量子硬件系统的局限性。该实施是开源的,可以在https://github.com/prince-ph0en1x/quaser上找到。

In this article, we present QuASeR, a reference-free DNA sequence reconstruction implementation via de novo assembly on both gate-based and quantum annealing platforms. Each one of the four steps of the implementation (TSP, QUBO, Hamiltonians and QAOA) is explained with simple proof-of-concept examples to target both the genomics research community and quantum application developers in a self-contained manner. The details of the implementation are discussed for the various layers of the quantum full-stack accelerator design. We also highlight the limitations of current classical simulation and available quantum hardware systems. The implementation is open-source and can be found on https://github.com/prince-ph0en1x/QuASeR.

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