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In reptiles, especially during their early stage of life when reared under captive conditions, nutritional deficiencies are the most common problems reported in them affecting the spinal cord and the musculoskeletal system. More often green iguanas and snakes are very much vulnerable to it. Case description: A three and a half months old green iguana (Iguana iguana) was brought to the Avian and Exotic Pet Unit, Madras Veterinary College with the history of dragging hind limbs and not passed faeces for the past four days. Findings, treatment and outcome: On examination of hind limbs, it was found that perching reflex was absent and the abdomen was distended. It was tentatively diagnosed for hind limb paralysis but the radiological examination revealed that the iguana was suffering from Sacro-coccygeal compression. The condition could have been aggravated due to poor nutritional management also. In order to reduce the pain, the iguana was treated with Meloxicam orally @ 0.1 mg/kg for a week. In addition, it was successfully treated orally with multivitamin syrup and calcium syrup simultaneously for a month. The iguana was subjected to infrared therapy of 3 minutes for a period of one week. The reptile showed complete recovery without dragging its hind limb after 2 months. Conclusion: It could be concluded that prompt intervention and dietary management may be necessary for musculo-skeletal disorders in Iguana. .