论文标题

磁体在磁性高温中的应用

Application of magnetosomes in magnetic hyperthermia

论文作者

Usov, N. A., Gubanova, E. M.

论文摘要

磁体,即通过磁性细菌在自然界合成的纳米颗粒,非常有前途用于磁性高温进行癌症治疗。使用随机Landau-Lifshitz方程的溶液,我们计算了磁体链组件的交替磁场中的特定吸收率,具体取决于粒径,链中的颗粒之间的距离以及相对于链轴的施加磁场的角度。特异性吸收率对链颗粒之间距离的依赖性显示为具有明显最大值的钟形式。最大比吸收率仅弱取决于纳米颗粒的直径和链的长度。但是,由于不同链的纳米颗粒的强磁极相互作用,在密集的链条组装中发生了明显降低。

Magnetosomes, i.e. nanoparticles synthesized in nature by magnetotactic bacteria, are very promising for use in magnetic hyperthermia for the cancer treatment. Using the solution of the stochastic Landau-Lifshitz equation we calculate the specific absorption rate in an alternating magnetic field of assemblies of magnetosome chains depending on the particle size, the distance between particles in a chain, and the angle of the applied magnetic field with respect to the chain axis. The dependence of specific absorption rate on the distance between the chain particles is shown to have a bell-shaped form with a pronounced maximum. The maximum specific absorption rate only weakly depends on the diameter of the nanoparticles and the length of the chain. However, a significant decrease in specific absorption rate occurs in a dense chain assembly due to the strong magneto-dipole interaction of nanoparticles of different chains.

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