论文标题
Scribble2Label:通过具有一致性的自我生成伪标记的涂鸦监督细胞分割
Scribble2Label: Scribble-Supervised Cell Segmentation via Self-Generating Pseudo-Labels with Consistency
论文作者
论文摘要
分割是微观细胞图像分析中的一个基本过程。随着深度学习最新进展的出现,更准确和高通量的细胞分割变得可行。但是,大多数现有的基于深度学习的细胞分割算法都需要完全注释的地面真实细胞标签,这些细胞标签既耗时又耗时。在本文中,我们介绍了Scribble2Label,这是一种新型弱监督的细胞分割框架,仅利用少数涂鸦注释而没有完整的分割标签。核心思想是将伪标记和标签过滤结合起来,以产生来自弱监督的可靠标签。为此,我们通过迭代平均预测以改善伪标签来利用预测的一致性。我们通过将其与几种具有各种细胞图像模态的最先进的细胞分割方法进行比较,包括涂鸦2个标签的性能,包括明亮场,荧光和电子显微镜。我们还表明,我们的方法在不同级别的涂鸦细节上执行强大的性能,这证实了在实际情况下只需要少量涂鸦注释。
Segmentation is a fundamental process in microscopic cell image analysis. With the advent of recent advances in deep learning, more accurate and high-throughput cell segmentation has become feasible. However, most existing deep learning-based cell segmentation algorithms require fully annotated ground-truth cell labels, which are time-consuming and labor-intensive to generate. In this paper, we introduce Scribble2Label, a novel weakly-supervised cell segmentation framework that exploits only a handful of scribble annotations without full segmentation labels. The core idea is to combine pseudo-labeling and label filtering to generate reliable labels from weak supervision. For this, we leverage the consistency of predictions by iteratively averaging the predictions to improve pseudo labels. We demonstrate the performance of Scribble2Label by comparing it to several state-of-the-art cell segmentation methods with various cell image modalities, including bright-field, fluorescence, and electron microscopy. We also show that our method performs robustly across different levels of scribble details, which confirms that only a few scribble annotations are required in real-use cases.