论文标题

在细胞极化模型中产生的抛物线无界边界问题

A parabolic free boundary problem arising in a model of cell polarization

论文作者

Logioti, Anna, Niethammer, Barbara, Röger, Matthias, Velázquez, Juan J. L.

论文摘要

外部信号的扩增是生物细胞方向传感的关键步骤。我们考虑了一个简单的模型,用于响应时间扩展信号,该模型以前是最后三位作者提出的。该模型由散装表面反应扩散模型组成。我们证明,在合适的渐近限制中,系统会收敛到散装抛物线障碍物类型问题。对于此模型,并减少了非局部表面方程,我们显示了L1征收特性,在时间稳定信号的情况下,我们显示了固定状态的稳定性。

The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model consists of a bulk-surface reaction-diffusion model. We prove that in a suitable asymptotic limit the system converges to a bulk-surface parabolic obstacle type problem. For this model and a reduction to a nonlocal surface equation we show an L1-contraction property and, in the case of time-constant signals, the stability of stationary states.

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