论文标题
临床贝叶斯网络开发的医学成语
Medical idioms for clinical Bayesian network development
论文作者
论文摘要
贝叶斯网络(BNS)是在医疗应用中被证明流行的图形概率模型。尽管已经发布了许多医学BN,但大多数人都在不解释网络结构是如何开发网络结构或证明其为何代表给定医疗应用的正确结构的理由的情况下出现的。这意味着从专家那里建立医疗BN的过程通常是临时的,几乎没有提供方法论上的改进机会。本文提出了通常适用且可重复使用的医学推理模式,以帮助人们开发医疗BN。所提出的方法补充并扩展了2000年Neil,Fenton和Nielsen引入的基于成语的方法。我们提出了针对医学BNS的通用成语的实例。我们将拟议的医学推理模式称为医学成语。此外,我们扩展了习语来表示介入和反事实推理。我们认为,拟议的医学习惯是逻辑上的推理模式,可以将,重复使用和普遍应用以帮助开发医疗BN。所有提出的医学习惯都使用有关冠状动脉疾病的医学例子进行了说明。该方法还应用于医学专家正在开发的其他BNS。最后,我们表明,将所提出的医学成语应用于已发表的BN模型导致结构更清晰的模型。
Bayesian Networks (BNs) are graphical probabilistic models that have proven popular in medical applications. While numerous medical BNs have been published, most are presented fait accompli without explanation of how the network structure was developed or justification of why it represents the correct structure for the given medical application. This means that the process of building medical BNs from experts is typically ad hoc and offers little opportunity for methodological improvement. This paper proposes generally applicable and reusable medical reasoning patterns to aid those developing medical BNs. The proposed method complements and extends the idiom-based approach introduced by Neil, Fenton, and Nielsen in 2000. We propose instances of their generic idioms that are specific to medical BNs. We refer to the proposed medical reasoning patterns as medical idioms. In addition, we extend the use of idioms to represent interventional and counterfactual reasoning. We believe that the proposed medical idioms are logical reasoning patterns that can be combined, reused and applied generically to help develop medical BNs. All proposed medical idioms have been illustrated using medical examples on coronary artery disease. The method has also been applied to other ongoing BNs being developed with medical experts. Finally, we show that applying the proposed medical idioms to published BN models results in models with a clearer structure.