论文标题
DNA与RNA - 显示出更高的电子传导？
DNA versus RNA -- which shows higher electronic conduction?
论文作者
论文摘要
在这项研究中，我们比较了与相应的dsDNA序列的多个（双链）dsRNA序列的电荷转运特性。最近的研究列出了A形DNA中相对电荷转运效率的矛盾图片：RNA杂交和DSDNA。使用多尺度建模框架，我们在连贯的极限和Marcus-Hush理论中使用Landauer形式主义计算DsDNA和DSRNA的电导，并以不一致的极限进行计算。我们发现，在两个电荷传输方案中，dsDNA的性能都比DSRNA更好。我们的分析表明，dsDNA和dsRNA的扭曲角度和载玻片上的结构差异是dsDNA在不连贯的跳跃方案中较高电导率的主要原因。然而，在相同的限值中，对于相同的碱基对长度，dsRNA的电导率高于dsDNA的电导，对于dsRNA而言，dsRNA相对于dsDNA的端到端长度较小。
In this study, we compare the charge transport properties of multiple (double stranded) dsRNA sequences with corresponding dsDNA sequences. Recent studies have presented a contradictory picture of relative charge transport efficiencies in A-form DNA:RNA hybrids and dsDNA. Using a multiscale modelling framework, we compute conductance of dsDNA and dsRNA using Landauer formalism in coherent limit and Marcus-Hush theory in the incoherent limit. We find that dsDNA conducts better than dsRNA in both the charge transport regimes. Our analysis shows that the structural differences in the twist angle and slide of dsDNA and dsRNA are the main reasons behind the higher conductance of dsDNA in the incoherent hopping regime. In the coherent limit however, for the same base pair length, the conductance of dsRNA is higher than that of dsDNA for the morphologies where dsRNA has smaller end-to-end length relative to that of dsDNA.
