论文标题
Metasub微生物组核心分析管道可实现大规模的元基因组分析
The MetaSUB Microbiome Core Analysis Pipeline Enables Large Scale Metagenomic Analysis
论文作者
论文摘要
动机：准确的数据分析和质量控制对于宏基因组研究至关重要。尽管存在许多分析宏基因组数据的工具，但是没有一致的框架可以在项目中集成和运行这些工具。当前，元基因组的计算分析很耗时，通常会错过潜在的有趣结果，并且很难繁殖。此外，工具和数据库中的不一致会阻碍元基因组研究之间的比较。 结果：我们介绍了Metasub核心分析管道（CAP）一个综合工具，用于分析元基因组并总结项目的结果。该帽子以自下而上的方式设计，以执行QC，预处理，分析，甚至构建相关数据库并安装必要的工具。 可用性和实施：CAP可在GitHub上的MIT许可证上获得，网址为https://github.com/metasub/cap2和Python软件包索引。文档和示例可在GitHub上找到。
Motivation: Accurate data analysis and quality control is critical for metagenomic studies. Though many tools exist to analyze metagenomic data there is no consistent framework to integrate and run these tools across projects. Currently, computational analysis of metagenomes is time consuming, often misses potentially interesting results, and is difficult to reproduce. Further, comparison between metagenomic studies is hampered by inconsistencies in tools and databases. Results: We present the MetaSUB Core Analysis Pipeline (CAP) a comprehensive tool to analyze metagenomes and summarize the results of a project. The CAP is designed in a bottom up fashion to perform QC, preprocessing, analysis and even to build relevant databases and install necessary tools. Availability and Implementation: The CAP is available under an MIT License on GitHub at https://github.com/MetaSUB/CAP2 and on the Python Package Index. Documentation and examples are available on GitHub.
