顶级项目的状态和发展

论文标题

顶级项目的状态和发展

Status and development of the TOP-IMPLART Project

论文作者

Picardi, L., Ampollini, A., Anello, P., Balduzzi, M., Bazzano, G., Borgognoni, F., Cisbani, E., DAndrea, M., De Angelis, C., De Angelis, G., Della Monaca, S., Esposito, G., Ghio, F., Giuliani, F., Lucentini, M., Marino, C., Montereali, R. M., Nenzi, P., Notaro, C., Patrono, C., Placido, C., Piccinini, M., Ronsivalle, C., Santavenere, F., Spurio, A., Strigari, L., Surrenti, V., Tabocchini, A., Trinca, E., Vadrucci, M.

论文摘要

顶级项目由线性质子加速器的设计和实施组成，即其控制和监测系统，用于治疗浅表和半深肿瘤。 150 MeV的能量（对应于15 cm的组织中的渗透）是设计的一个里程碑，可用于质子治疗基于其位置和深度的近50％的肿瘤治疗（包括眼部黑色素瘤，头颈肿瘤，儿科肿瘤，以及更多的浅表肿瘤）。与电子反馈系统相结合的脉冲对脉冲基础的强度的能力使得获得所需的剂量均匀性（2.5％）减少重新绘制的数量。在本文中，在Protontherapy进展的框架内描述了艺术的状态和顶级项目的目标。

The TOP-IMPLART project consists of the design and implementation of a linear proton accelerator, its control and monitoring systems for the treatment of superficial and semi-deep tumors. The energy of 150 MeV (corresponding to a penetration in tissue of about 15 cm) is a milestone in design being useful for the proton therapy treatment of almost 50% of tumors based on their position and depth (including ocular melanoma, head-neck tumors, pediatric tumors, and more superficial tumors). The capability to vary the intensity on a pulse-to-pulse basis combined with an electronic feedback system allows to get the required dose uniformity (2.5%) reducing the number of re-paintings. In this paper the state of the art and the objectives of the TOP-IMPLART project are described within the framework of the progress of Protontherapy.

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