论文标题
用于医学成像的扩散超声计算机断层扫描
Diffuse ultrasound computed tomography for medical imaging
论文作者
论文摘要
提出了用于进行医学成像的超声计算机断层扫描(USCT)的替代方法,目的是(i)缩短具有大量发射器的设备的获取时间,(ii)消除校准步骤,(iii)抑制仪器噪声。受地震环境场干涉仪的启发,该方法取决于弥漫性超声波场的主动激发,并通过施加间相关性提取确定性旅行时间信息。为了减少随机误差和加速收敛,通过相位加权的堆叠观察到的相关图和计算的相关图获得了集合干涉图,并以随机源的相同实现生成。模仿乳房成像设置,可以通过分析和光谱 - 元素模拟对现实的乳房幻象进行分析和光谱元素模拟来评估旅行时间测量的准确性和发射器数量的函数和随机实现的函数。结果保留使用直射线或弯曲射线方法的层析成像重建,其中固有的随机波动的影响可以明显小于主观选择对正则化的影响。这项工作构成了第一个概念研究,也是未来实施的必要前奏。
An alternative approach to ultrasound computed tomography (USCT) for medical imaging is proposed, with the intent to (i) shorten acquisition time for devices with a large number of emitters, (ii) eliminate the calibration step, and (iii) suppress instrument noise. Inspired by seismic ambient field interferometry, the method rests on the active excitation of diffuse ultrasonic wavefields and the extraction of deterministic travel time information by inter-station correlation. To reduce stochastic errors and accelerate convergence, ensemble interferograms are obtained by phase-weighted stacking of observed and computed correlograms, generated with identical realizations of random sources. Mimicking a breast imaging setup, the accuracy of the travel time measurements as a function of the number of emitters and random realizations can be assessed both analytically and with spectral-element simulations for realistic breast phantoms. The results warrant tomographic reconstructions with straight- or bent-ray approaches, where the effect of inherent stochastic fluctuations can be made significantly smaller than the effect of subjective choices on regularisation. This work constitutes a first conceptual study and a necessary prelude to future implementations.