论文标题

质子治疗中每日质量保证测量的像素化硅探测器的表征

Characterization of pixelated silicon detectors for daily quality assurance measurements in proton therapy

论文作者

Schilling, Isabelle, Bäcker, Claus Maximillian, Bäumer, Christian, Behrends, Carina, Kröninger, Kevin, Timmermann, Beate, Weingarten, Jens

论文摘要

质子疗法中的高级成像和输送技术允许使用铅笔梁扫描或梁成型孔高精度对目标体积进行共形高剂量照射。这些辐照方法越来越多地包括具有较大剂量梯度的小辐射场,这些辐射场需要具有高空间分辨率的检测器系统才能进行质量保证。此外,仅使用一个质子场和一个简单的检测器系统来测量所有成功参数,以进行日常质量保证,将节省大量时间的临床用法。基于它们良好的空间分辨率和高率兼容性,像素化的硅探测器可以满足新的要求。为了评估其在质子疗法中的适用性,使用高空间分辨率的地图集的硅探测器来测量侧束轮廓。此外,提出了依赖剂量的检测器校准,以允许测量所需的输出恒定恒定。正在研究每日质量保证期间验证质子能量的策略。在德国埃森的西德质子疗法中心的原理证明测量结果已获得有希望的结果。

The advanced imaging and delivery techniques in proton therapy allow conformal high-dose irradiation of the target volume with high accuracy using pencil beam scanning or beam shaping apertures. These irradiation methods increasingly include small radiation fields with large dose gradients, which require detector systems with high spatial resolution for quality assurance. In addition the measurement of all success parameters for daily quality assurance with only one proton field and one simple detector system would save a lot of time in clinical usage. Based on their good spatial resolution and high rate compatibility, pixelated silicon detectors could meet the new requirements. To assess their applicability in proton therapy, ATLAS pixelated silicon detectors are used to measure the lateral beam profile with high spatial resolution. Furthermore, a dose dependent detector calibration is presented to allow the measurement of the requested output constancy. A strategy to verify the proton energy during the daily quality assurance is under study. Promising results from proof-of-principle measurements at the West German Proton Therapy Centre in Essen, Germany, have been obtained.

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