论文标题

粒子治疗中质子146通道计数器的数据采集系统

Data acquisition system for a 146-channel counter of protons in particle therapy

论文作者

Giordanengo, S., Abujami, M., Galeone, C., Garbolino, S., Villarreal, O. A. Martì, Milian, F. Mas, Mazza, G., Mignone, M., Vignati, A., Wheadon, R., Cirio, R., Monaco, V., Sacchi, R.

论文摘要

质子计数器的原型是由大学和美国国家核物理研究所开发的,用于在粒子疗法中用作在线通电束监测器。单个粒子识别方法旨在提高相对于最先进的气体电离室的灵敏度和读数速度。敏感区域为2,7 x 2,7 cm^2,以覆盖临床束横截面,其特征在于,其特征是在同伴处最大约1 cm的全宽度。传感器是一个薄的低增益雪崩二极管,在146条带有180微米螺距和50微米的活动厚度中分割,由Fondazione Bruno Kessler(意大利Trento)设计和生产。识别每个条带提供的单个质子信号的前端读数基于24渠道自定义ASIC,称为Abacus,优化以区分宽电荷范围内的信号脉冲(3-150 fc),最大死亡时间为10 ns。根据这些规格,在临床能量范围(60-230 MeV)中的10^8 p/(cm^2s)的最大通量速率下,考虑到上述硅条,最大堆积的计数效率低于1%。一个前端板容纳了6个算盘芯片,用于读取146条带,将数字输出发送到3 fpgas(Kintex7)进行计数。 LabView程序实现了与FPGA的接口,在线显示每个条带的计数率,并存储数据以进行离线分析。

A prototype of proton counter was developed by the University and the National Institute for Nuclear Physics of Torino to be used as online fluence beam monitor in particle therapy. The single particle identification approach aims at increasing the sensitivity and readout speed with respect to the state-of-the-art gas ionization chambers. The sensitive area is 2,7 x 2,7 cm^2 to cover the clinical beam cross section characterized by a full width at half maximum of about 1 cm at the isocenter. The sensor is a thin Low Gain Avalanche Diode segmented in 146 strips with 180 micrometer pitch and with 50 micrometer active thickness, designed and produced by the Fondazione Bruno Kessler (Trento, Italy). The frontend readout to identify the single proton signal provided by each strip is based on a 24channel custom ASICs, named ABACUS, optimized to discriminate the signal pulses in a wide charge range (3-150 fC) with a maximum dead-time of 10 ns. With these specifications, at the maximum fluence rate of 10^8 p/(cm^2s) in the clinical energy range (60-230 MeV) and considering the silicon strips described above, a maximum pileup counting inefficiency less than 1 percent is achieved. A frontend board housing 6 ABACUS chips to readout the 146 strips was developed, the digital outputs being sent to 3 FPGAs (Kintex7) for the counting. A LabVIEW program implements the interface with the FPGAs, displays online the counting rate from each strip and stores the data for offline analysis.

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