论文标题
由三态基因产生随机mRNA
Stochastic mRNA production by a three-state gene
论文作者
论文摘要
我们考虑了一个由三个可能的状态中存在的基因的动力学控制的mRNA产生模型 - 不活跃,有现状和活跃。相邻状态之间的过渡由以相应的/OFF速率为特征的随机过程控制。仅当基因处于活性状态时,才会产生mRNA,我们还考虑导致其死亡的mRNA变性。
We consider a model of mRNA production governed by the dynamics of a gene that exists in three possible states -- inactive, poised and active. The transitions between the adjacent states are controlled by stochastic processes characterized by corresponding on/off rates. mRNA is produced only when the gene is in active state and we also consider mRNA denaturation leading to its death.