论文标题
基于代理的医学研究建模。卫生经济学的例子
Agent-Based modeling in Medical Research. Example in Health Economics
论文作者
论文摘要
本章介绍了医学研究领域基于代理的建模的主要建模。一般图由一组患者（虚拟或真实）组成，其进化是通过所谓的进化模型观察到的。然后可以通过改变不同模型的参数来探索场景。本章介绍了虚拟患者生成的技术和执行模型的示例。讨论了这些模型的优势和缺点，以及避免的陷阱。最后，提出了对医学经济学研究的应用，该研究介绍了通用版本的渗透率对与HIV治疗相关的成本的渗透率。
This chapter presents the main lines of agent based modeling in the field of medical research. The general diagram consists of a cohort of patients (virtual or real) whose evolution is observed by means of so-called evolution models. Scenarios can then be explored by varying the parameters of the different models. This chapter presents techniques for virtual patient generation and examples of execution models. The advantages and disadvantages of these models are discussed as well as the pitfalls to be avoided. Finally, an application to the medico-economic study of the impact of the penetration rate of generic versions of treatments on the costs associated with HIV treatment is presented.
