论文标题

张力链的出现和主动力模式

Emergence of Tension Chains and Active Force Patterning

论文作者

Roychowdhury, Ayan, Dasgupta, Saptarshi, Rao, Madan

论文摘要

在荧光显微镜下观察,肌动蛋白细胞骨架表现出生动的线条和持续的振荡波。使用主动流体动力学方法,我们展示了收缩应激的单个或混合物的均匀分布自发地分离,然后在有限的时间内形成高收缩链(张力链)的奇异结构。同时,压力集的集合表现出行进波和由于非肾脏的交换而交换。在单元格的有限几何形状中,主动张力链的收集可以形成一个活跃的网络,通过在细胞边界处的特定锚固组合在一起。另一方面,在细胞边界处的优先润湿可以加强压力聚集的混合物中的活性隔离,从而导致分层。

Viewed under a fluorescence microscope, the actomyosin cytoskeleton presents vivid streaks of lines together with persistent oscillatory waves. Using an active hydrodynamic approach, we show how a uniform distribution of single or mixture of contractile stresslets spontaneously segregate, followed by the formation of singular structures of high contractility (tension chains) in finite time. Simultaneously, the collection of stresslets exhibit travelling waves and swapping as a consequence of nonreciprocity. In the finite geometry of the cell, the collection of active tension chains can form an active web held together by specific anchoring at the cell boundary. On the other hand, preferential wetting at the cell boundary can reinforce active segregation in a mixture of stresslets leading to stratification.

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