论文标题

心肌分割的深度统计形状模型

Deep Statistic Shape Model for Myocardium Segmentation

论文作者

Hu, Xiaoling, Chen, Xiao, Liu, Yikang, Chen, Eric Z., Chen, Terrence, Sun, Shanhui

论文摘要

心肌的准确分割和运动估计在临床领域一直很重要,这基本上有助于下游诊断。但是,现有方法不能总是保证心肌分割的形状完整性。此外,运动估计需要在不同帧上对心肌区域的点对应关系。在本文中,我们提出了一种新型的端到端深度统计形状模型,以关注具有形状完整性和边界对应关系的心肌分割。具体而言,心肌形状由固定数量的点表示,其变化是通过主成分分析(PCA)提取的。深神经网络用于预测转换参数(仿射和变形),然后将其用于将平均点云绕到图像域。此外,引入了一个可区分的渲染层,以将掩模的监督纳入框架中,以了解更准确的点云。通过这种方式,所提出的方法能够在不进行后处理的情况下始终如一地产生解剖上合理的分割掩码。此外,预测的点云还保证了顺序图像的边界对应关系,这有助于下游任务,例如心肌运动估计。我们进行了几项实验,以证明在几个基准数据集上提出的方法的有效性。

Accurate segmentation and motion estimation of myocardium have always been important in clinic field, which essentially contribute to the downstream diagnosis. However, existing methods cannot always guarantee the shape integrity for myocardium segmentation. In addition, motion estimation requires point correspondence on the myocardium region across different frames. In this paper, we propose a novel end-to-end deep statistic shape model to focus on myocardium segmentation with both shape integrity and boundary correspondence preserving. Specifically, myocardium shapes are represented by a fixed number of points, whose variations are extracted by Principal Component Analysis (PCA). Deep neural network is used to predict the transformation parameters (both affine and deformation), which are then used to warp the mean point cloud to the image domain. Furthermore, a differentiable rendering layer is introduced to incorporate mask supervision into the framework to learn more accurate point clouds. In this way, the proposed method is able to consistently produce anatomically reasonable segmentation mask without post processing. Additionally, the predicted point cloud guarantees boundary correspondence for sequential images, which contributes to the downstream tasks, such as the motion estimation of myocardium. We conduct several experiments to demonstrate the effectiveness of the proposed method on several benchmark datasets.

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