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We propose StyleTalker, a novel audio-driven talking head generation model that can synthesize a video of a talking person from a single reference image with accurately audio-synced lip shapes, realistic head poses, and eye blinks. Specifically, by leveraging a pretrained image generator and an image encoder, we estimate the latent codes of the talking head video that faithfully reflects the given audio. This is made possible with several newly devised components: 1) A contrastive lip-sync discriminator for accurate lip synchronization, 2) A conditional sequential variational autoencoder that learns the latent motion space disentangled from the lip movements, such that we can independently manipulate the motions and lip movements while preserving the identity. 3) An auto-regressive prior augmented with normalizing flow to learn a complex audio-to-motion multi-modal latent space. Equipped with these components, StyleTalker can generate talking head videos not only in a motion-controllable way when another motion source video is given but also in a completely audio-driven manner by inferring realistic motions from the input audio. Through extensive experiments and user studies, we show that our model is able to synthesize talking head videos with impressive perceptual quality which are accurately lip-synced with the input audios, largely outperforming state-of-the-art baselines.