论文标题
瞬时神经事件中因果影响的信息理论措施
Information Theoretic Measures of Causal Influences during Transient Neural Events
论文作者
论文摘要
瞬态现象在多个尺度上协调大脑活性方面起着关键作用，但是，它们的潜在机制在很大程度上仍然未知。因此，神经数据科学的一个主要挑战是表征这些事件期间的网络交互。使用结构性因果模型的形式主义及其图形表示，我们研究了基于信息理论的理论和经验特性，基于信息理论的因果力量测量在反复自发的瞬态事件的背景下。在这种环境中显示了转移熵和动态因果强度的局限性之后，我们引入了一种新颖的措施，相对动态的因果强度，并为其益处提供了理论和经验支持。这些方法应用于模拟和实验记录的神经时间序列，并与我们当前对潜在脑电路的理解相吻合。
Transient phenomena play a key role in coordinating brain activity at multiple scales, however,their underlying mechanisms remain largely unknown. A key challenge for neural data science is thus to characterize the network interactions at play during these events. Using the formalism of Structural Causal Models and their graphical representation, we investigate the theoretical and empirical properties of Information Theory based causal strength measures in the context of recurring spontaneous transient events. After showing the limitations of Transfer Entropy and Dynamic Causal Strength in such a setting, we introduce a novel measure, relative Dynamic Causal Strength, and provide theoretical and empirical support for its benefits. These methods are applied to simulated and experimentally recorded neural time series, and provide results in agreement with our current understanding of the underlying brain circuits.
