论文标题

Medigan:医学图像合成的预验证生成模型的Python库

medigan: a Python library of pretrained generative models for medical image synthesis

论文作者

Osuala, Richard, Skorupko, Grzegorz, Lazrak, Noussair, Garrucho, Lidia, García, Eloy, Joshi, Smriti, Jouide, Socayna, Rutherford, Michael, Prior, Fred, Kushibar, Kaisar, Diaz, Oliver, Lekadir, Karim

论文摘要

生成模型生成的合成数据可以增强医学成像中渴望数据深度学习模型的性能和能力。但是,(1)(合成)数据集的可用性有限,并且(2)生成模型训练很复杂,这阻碍了它们在研究和临床应用中的采用。为了减少此入口障碍,我们提出了Medigan,Medigan是一站式商店,用于验证的生成模型,该型号是开源框架 - 不合骨python图书馆。 Medigan允许研究人员和开发人员仅在几行代码中创建,增加和域名。在基于收集的最终用户需求的设计决策的指导下,我们基于生成模型的模块化组件(i)执行,(ii)可视化,(iii)搜索和排名以及(iv)贡献。图书馆的可伸缩性和设计是通过其越来越多的集成且易于使用的预审预周化的生成模型来证明的,该模型由21个模型组成,利用9种不同的生成对抗网络体系结构在4个域中在11个数据集中训练,即乳腺摄影,内窥镜检查,X射线和MRI。此外,在这项工作中分析了Medigan的3个应用,其中包括(a)启用社区范围内的限制数据共享,(b)研究生成模型评估指标以及(c)改进临床下游任务。在(b)中,根据图像归一化和放射学特异性特征提取,我们显示了Fréchet距离变异性的扩展,我们显示了Fréchet成立距离变异性。

Synthetic data generated by generative models can enhance the performance and capabilities of data-hungry deep learning models in medical imaging. However, there is (1) limited availability of (synthetic) datasets and (2) generative models are complex to train, which hinders their adoption in research and clinical applications. To reduce this entry barrier, we propose medigan, a one-stop shop for pretrained generative models implemented as an open-source framework-agnostic Python library. medigan allows researchers and developers to create, increase, and domain-adapt their training data in just a few lines of code. Guided by design decisions based on gathered end-user requirements, we implement medigan based on modular components for generative model (i) execution, (ii) visualisation, (iii) search & ranking, and (iv) contribution. The library's scalability and design is demonstrated by its growing number of integrated and readily-usable pretrained generative models consisting of 21 models utilising 9 different Generative Adversarial Network architectures trained on 11 datasets from 4 domains, namely, mammography, endoscopy, x-ray, and MRI. Furthermore, 3 applications of medigan are analysed in this work, which include (a) enabling community-wide sharing of restricted data, (b) investigating generative model evaluation metrics, and (c) improving clinical downstream tasks. In (b), extending on common medical image synthesis assessment and reporting standards, we show Fréchet Inception Distance variability based on image normalisation and radiology-specific feature extraction.

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